| 2022-03-14 19:00:20March 14, 2022 |   Blacksburg — Franklin County | 9 - 0 | Franklin County High School | Recap |
| 2022-03-16 17:30:17March 16, 2022 |  Blacksburg — Radford | 7 - 0 | Blacksburg High School | Recap |
| 2022-03-21 19:00:46March 21, 2022 |  Blacksburg — Hidden Valley | 6 - 2 | Hidden Valley High School | Recap |
| 2022-03-25 19:00:43March 25, 2022 |  Blacksburg — Cave Spring | 7 - 0 | Cave Spring High School | Recap |
| 2022-03-28 19:00:18March 28, 2022 | Blacksburg — Franklin County | 6 - 0 | Blacksburg High School | Recap |
| 2022-04-05 19:00:17April 5, 2022 |  Blacksburg — Pulaski | 10 - 0 | Pulaski County High School | Recap |
| 2022-04-08 19:00:28April 8, 2022 |  Blacksburg — Patrick Henry | 8 - 0 | Blacksburg High School | Recap |
| 2022-04-11 19:00:47April 11, 2022 |  Blacksburg — Salem | 5 - 0 | Blacksburg High School | Recap |
| 2022-04-20 19:00:35April 20, 2022 |  Blacksburg — Christiansburg | 7 - 0 | Blacksburg High School | Recap |
| 2022-04-22 19:00:39April 22, 2022 | Blacksburg — Hidden Valley | 6 - 0 | Blacksburg High School | Recap |
| 2022-04-25 19:00:16April 25, 2022 |  Blacksburg — Harrisonburg | 9 - 0 | Harrisonburg High School | Recap |
| 2022-04-26 19:00:31April 26, 2022 | Blacksburg — Cave Spring | 7 - 0 | Blacksburg High School | Recap |
| 2022-05-03 19:00:28May 3, 2022 | Blacksburg — Salem | 2 - 0 | Salem High School | Recap |
| 2022-05-05 19:00:06May 5, 2022 | Blacksburg — Pulaski | 11 - 0 | Blacksburg High School | Recap |
| 2022-05-10 19:00:31May 10, 2022 | Blacksburg — Patrick Henry | 6 - 0 | Patrick Henry High School | Recap |
| 2022-05-12 19:00:29May 12, 2022 | Blacksburg — Christiansburg | 5 - 0 | Christiansburg High School | Recap |
| 2022-05-18 19:00:55May 18, 2022 | River Ridge District Final | 2 - 1 | Virginia Tech Thompson Field | Recap |
| 2022-05-26 19:00:15May 26, 2022 |  Region 4D West Quarter Final | 8 - 0 | Blacksburg High School | Recap |
| 2022-05-31 19:00:02May 31, 2022 |  Region 4D West Semi Final | 1 - 0 | Blacksburg High School | Recap |
| 2022-06-02 19:00:26June 2, 2022 | Region 4D West Final | 1 - 0 | Blacksburg High School | Recap |
| 2022-06-07 18:00:27June 7, 2022 |  VHSL State Quarter Final | 1 - 2 | Blacksburg High School | Recap |
